How Urticaria antihistamines work?
If you have ever had a skin allergy due to mast cells and histamines, especially urticaria, then you will have heard about antihistamines.
A urticaria antihistamine is a drug that counteracts the effects of the histamines that cause urticaria. However the urticaria antihistamines do not treat the underlying cause of urticaria. They just provide temporary relief to the patient from the itching or burning sensation and they are not considered to be a permanent urticaria treatment.
Though they relieve the patient of his itching, you still need to be careful about many things related to urtiacria antihistamines, read here to learn about these precautions in my article.
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An urticaria antihistamine is a drug that counteracts the effects of histamines that cause urticaria. However, urticaria antihistamines do not treat the underlying causes of urticaria. They only provide temporary relief from the itching or burning sensation and are not considered to be a permanent urticaria treatment.
Histamines are released by the mast cells, which are widespread throughout the skin. When these mast cells are triggered by certain stimuli, they release histamines into the adjacent area of the skin. These histamines then cause rashes, itching, burning sensations, swelling, and other problems according to the nature of the stimulus. These skin problems are called urticaria.
There are four major types of histamines defined by medical science: H1, H2, H3, and H4. Furthermore, H3 and H4 antihistamines are not used in common clinical practice and are merely used for experimental purposes. H1 and H2 antihistamines are inverse agonists. H2 antihistamines are usually used to reduce the secretion of gastric acid and to treat other gastrointestinal conditions, including peptic ulcers and gastroesophageal reflux disease.
H1 antihistamines are used to treat allergic reactions, including different types of urticaria. Other uses of H1 antihistamines include reducing local inflammation that occurs due to various conditions, such as insect stings, even if there is no allergic reaction. Some antihistamines can cause drowsiness; therefore, activities that require mental and physical vigilance should be avoided after taking them.
Remember that antihistamines are used to provide the patient temporary relief, and patients should avoid their permanent use, as some of them are addictive.
